Effects and suspicion of brain coma and brain death patients

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Traumatic brain injuries are a recurrent problem in emergency rooms. Concerning cerebral haemorrhage incidents and their ensuing consequences which brain death is the end of the clinical scenario they are of significance. The permanent loss of breathing and blood circulation has been used to define mass extinction as a unit. It was fundamentally altered the assumptions of contemporary medicine to expand the definition of death to include individuals with severe brain damage. Medical evidence that this phenomenon is irreversible should be shown at any point during its existence. Most of the time, a diagnosis of brain death can only be made after a thorough clinical examination and assessment of the origins, processes, and consequences of brain injury. Lab trials that can diagnose brain death cannot be carried out or properly interpreted in cases of subtentorial brain damage, severe facial injuries, the presence of aberrant neurologic impulses, and scenarios in which the patient is exposed to certain toxins or specific pharmaceutical agents. Then, other tests, including cerebral arteriography, which are not always accessible, are required to complete the diagnosis process. It should be mentioned that laboratory diagnostics still haven't shown themselves to be effective in these circumstances. Recognition of brain death, or at least suspicion of it, may mirror in certain situations the prognosis of a myocardial ischemia, where serum troponin levels play a crucial role.

These changes could be subtle, such as a disruption in the quantitative relationship between various chemical compounds, or they could be more obvious, like the emergence of completely new chemical compounds or the disappearance of particular molecules that are essential to homeostasis. The supposed potential of only two proteins-protein and neuron-specific enolase-has so far been reported; however, these are simply single findings, and no extensive investigation using cutting-edge proteomic techniques has yet been carried out. Despite the severity of the issue, this theme is somewhat uncharted territory in medicine; there are hardly any scholarly papers on the topic, and it appears that developing new techniques for diagnosing brain abnormalities is an essential requirement. The idea behind metabolomics research is based on the fact that as regional and systemic psychopathic processes progress, the first diagnosis that manifest at the cellular level are directly reflected in the chemical makeup of the body tissue that are being affected by these processes as well as in biological fluids.